Presents new ways of creating ions of polar and labile biopolymeric species with remarkable ease and efficiency. Introduces better characterization of proteins and other biological molecules. Presents major fundamental issues in such areas as immunology, biochemistry, and natural toxins. Demonstrates methods used to resolve the data from various biological process investigations into useful information. Provides an application-driven approach, presenting valuable insights into the experiments in the volume.

Biochemical and Biotechnological Applications of Electrospray Ionization Mass Spectrometry (ACS Symposium Series)

Snyder, A. Peter, 1952-; American Chemical Society. Division of Analytical Chemistry; American Chemical Society. Meeting (209th: 1995: Anaheim, Calif.)

A. Peter Snyder; American Chemical Society Division of Analytical Chemistry; American Chemical Society Meeting (209th : 1995 : Anaheim, Calif)

Washington, DC: American Chemical Society

ACS symposium series,, 619, Washington, DC, District of Columbia, February 17, 1998

ACS symposium series, Washington, DC, 1995 [erschienen] 1996

ACS symposium series, 619, Washington, DC, 1995

ACS symposium series, 619, Washington, DC, 1996

United States, United States of America

Includes bibliographical references and indexes.
"Developed from a symposium sponsored by the Division of Analytical Chemistry at the 209th National Meeting of the American Chemical Society, Anaheim, California, April 2-6, 1995."

xii, 601 pages : 24 cm
"Developed from a symposium sponsored by the Division of Analytical Chemistry at the 209th National Meeting of the American Chemical Society, Anaheim, California, April 2-6, 1995."
Includes bibliographical references and indexes
Electrospray, a popular ionization technique for mass spectrometry / A. Peter Snyder -- Analytical characteristics of the electrospray ionization process / Thomas Covey -- Electrospray ion formation : desorption versus desertion / J.B. Fenn, J. Rosell, T. Nohmi, S. Shen, and F.J. Banks, Jr. -- Liquid chromatography with electrospray ionization tandem mass spectrometry : profiling carbohydrates in whole bacterial cell hydrolysates / Gavin E. Black and Alvin Fox -- Identification of a cytoplasmic peptidoglycan precursor in antibiotic-resistant bacteria / Mike S. Lee, Kevin J. Volk, Jinping Liu, Michael J. Pucci, and Sandra Handwerger -- Structural characterization of prokaryotic glycans and oligosaccharides / Vernon N. Reinhold and Bruce B. Reinhold -- Structural characterization of lipopolysaccharides from Pseudomonas aeruginosa using capillary electrophoresis electrospray ionization mass spectrometry and tandem mass spectrometry / S. Auriola, P. Thibault, I. Sadovskaya, E. Altman, H. Masoud, and J.C. Richards -- Determining structures and functions of surface glycolipids in pathogenic Haemophilus bacteria by electrospray ionization mass spectrometry / Bradford W. Gibson, Nancy J. Phillips, William Melaugh, and Jeffrey J. Engstrom -- Electrospray ionization mass spectrometry for structural characterization of the lipid A component in bacterial endotoxins / Richard B. Cole -- Microcolumn liquid chromatography-electrospray ionization tandem mass spectrometry : analysis of immunological samples / Ashley L. McCormack, Jimmy K. Eng, Paul C. DeRoos, Alexander Y. Rudensky, and John R. Yates, III -- Identification of proteins from two-dimensional electrophoresis gels by peptide mass fingerprinting / David P. Arnott, William J. Henzel, and John T. Stults -- Lipid metabolism of the mosquito pathogen Lagenidium giganteum and its hosts : glycerophospholipids and hydroxy fatty acids / James L. Kerwin -- Characterization of polyunsaturated phospholipid remodeling in mammalian cells by high-performance liquid chromatography-electrospray ionization mass spectrometry / Hee-Yong Kim, Tao-Chin Lin Wang, and Yee-Chung Ma -- Application of electrospray ionization mass spectrometry to the analysis of oligodeoxynucleotides / Charles R. Iden, Robert A. Rieger, M. Cecilia Torres, and LeRoy B. Martin -- Noncovalent complexes of nucleic acids and proteins studied by electrospray ionization mass spectrometry / Richard D. Smith, Xueheng Cheng, Brenda L. Schwartz, Ruidan Chen, and Steven A. Hofstadler -- Analysis of xanomeline, a potential drug for Alzheimer's disease, by electrospray ionization tandem mass spectrometry / Todd A. Gillespie, Thomas J. Lindsay, J. David Cornpropst, Peter L. Bonate, Theresa G. Skaggs, Allyn F. DeLong, and Lisa A. Shipley -- High-performance liquid chromatography with atmospheric pressure ionization tandem mass spectrometry as a tool in quantitative bioanalytical chemistry / John D. Gilbert, Timothy V. Olah, and Debra A. McLoughlin -- Analysis of diarrhetic shellfish poisoning toxins and metabolites in plankton and shellfish by ion-spray liquid chromatography-mass spectrometry / M.A. Quilliam and N.W. Ross -- Identification of active-site residues in glycosidases / Stephen G. Withers -- Electrospray ionization mass spectrometric investigation of signal transduction pathways : determination of sites of inducible protein phosphorylation in activated T cells / Julian D. Watts, Michael Affolter, Danielle L. Krebs, Ronald L. Wange, Lawrence E. Samelson, and Ruedi Aebersold -- Characterization of recombinant glycoproteins from Chinese hamster ovary cells / Michael F. Rohde, Viswanatham Katta, Patricia Derby, and Robert S. Rush -- Complications in the determination of molecular weights of proteins and peptides using electrospray ionization mass spectrometry / Catherine Fenselau and Michele Kelly -- Use of hyphenated liquid-phase analyses-mass spectrometric approaches for the characterization of glycoproteins derived from recombinant DNA / A. Apffel, J. Chakel, S. Udiavar, W.S. Hancock, C. Souders, and E. Pungor, Jr. -- From protein primary sequence to the gamut of covalent modifications using mass spectrometry / A.L. Burlingame, K.F. Medzihradszky, K.R. Clauser, S.C. Hall, D.A. Maltby, and F.C. Walls -- Analysis of biomolecules using electrospray ionization-ion-trap mass spectrometry and laser photodissociation / James L. Stephenson, Jr., Matthew M. Booth, Stephen M. Boué, John R. Eyler, and Richard A. Yost -- Atmospheric pressure ionization liquid chromatography-mass spectrometry for environmental analysis / Robert D. Voyksner

This work presents new ways of creating ions of polar and labile biopolymeric species with ease and efficiency. It introduces better characterization of proteins and other biological molecules, and presents the use and application of ESI-MS as opposed to theory and fundamentals.

2023-06-28