In __Clinical Bioinformatics, Second Edition__,leading experts in the field provide a series of articles focusing on software applications used to translate information into outcomes of clinical relevance. Recent developments in __omics__, such as increasingly sophisticated analytic platforms allowing changes in diagnostic strategies from the traditional focus on single or small number of analytes to what might be possible when large numbers or all analytes are measured, are now impacting patient care. Covering such topics as gene discovery, gene function (microarrays), DNA sequencing, online approaches and resources, and informatics in clinical practice, this volume concisely yet thoroughly explores this cutting-edge subject. Written in the successful __Methods in Molecular Biology__ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.
Authoritative and easily accessible, __Clinical Bioinformatics, Second Edition__ serves as an ideal guide for scientists and health professionals working in genetics and genomics.

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Methods in Molecular Biology, Methods and Protocols, 2nd ed. 2014, New York, NY, 2014

Methods in molecular medicine -- 1168, Second Edition., New York, New Jersey, 2014

Methods in molecular biology (Clifton, N.J.), v. 1168, 2nd ed, New York, 2014

Methods in molecular biology (Clifton, N.J.), Second edition, New York, 2014

Methods in molecular biology, 2nd ed, New York ; Heidelberg, 2014

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From the phenotype to the genotype via bioinformatics / Cali E. Willet and Calire M. Wade
Production and analytic bioinformatics for next-generation DNA sequencing / Richard James, Nigel Allcock
Analyzing the metabolome / Fracnis G. Bowling and Mervyn Thomas
Statistical perspectives for Genome-Wide Association Studies (GWAS) / Jennifer H. Barrett, John C. Taylor, and Mark M. Iles
Bioinformatics challenges in Genome-Wide Association Studies (GWAS) / Rishika De, William S. Bush, and Jason H. Morre
Studying cancer genomics through next-generation DNA sequencing and bioinformatics / Maraia A. Doyle, Jason LI, Ken Doig, Andrew Fellowes, and Stephen Q. Wong - Using bioinformatics tools to study the role of microRNA in cancer / Fabio Passetti, Natasha Andressa Noguiera Jorge, and Alan Durham
Chromosome microarrays in diagnostic testing : interpreting the genomic data / Greg B. Peters and Mark D. Pertile
Bioinformatics approach to understanding interacting pathways in neuropsychiatric disorders / Ali Alawieh, Zahraa Sabra, Amaly Nokkari, Atlal El-Assaad, Stefania Mondello, Fadi Zaraket, Bilal Fadlallah, and Firas H. Kobeissy
Pathogen genome bioinformatics / Vitali Sintchenko and Michael P.V. Roper
Setting up next-generation sequencing in the medical laboratory / Bing Yu
Managing Incidental findings in Exome sequencing for research / Marcus J. Hinch cliffe
Approaches for classifying DNA variants found by Sanger sequencing in Medical Genetics Laboratory / Pak Leng Cheong and Melody Caramins
Designing algorithms for determining significance of DNA Missense changes / Sivakumar Gowrisankar and Matthew S. Lebo
DNA variant databases : current state and future directions / John-Paul Plazzer and Finalay Macrae
Natural language processing in biomedecine : a unified system architecture overview / Son Doan, Mike Conway, Tu Minh Phuong, and Lucila Ohno-Machado
Candidate gene discovery and prioritization in rare diseases / Anil G. Jegga
Computer-aided drug designing / Mohini Gore and Neetin S. Desai.

In Clinical Bioinformatics, Second Edition , leading experts in the field provide a series of articles focusing on software applications used to translate information into outcomes of clinical relevance. Recent developments in omics , such as increasingly sophisticated analytic platforms allowing changes in diagnostic strategies from the traditional focus on single or small number of analytes to what might be possible when large numbers or all analytes are measured, are now impacting patient care. Covering such topics as gene discovery, gene function (microarrays), DNA sequencing, online approaches and resources, and informatics in clinical practice, this volume concisely yet thoroughly explores this cutting-edge subject. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.
Authoritative and easily accessible, Clinical Bioinformatics, Second Edition serves as an ideal guide for scientists and health professionals working in genetics and genomics.

Front Matter....Pages i-xi
Back Matter....Pages 1-16
....Pages 17-29

Methods in Molecular Biology
Erscheinungsdatum: 28.05.2014

2014-06-01