Aging is one of the most serious and costly health problems in the Western world. A disproportionate amount of the available health care capability is devoted to the health care of the aged and the cost of this care is soaring. Viewed in wide perspective, aging presents two problems for the researcher's consideration. First is that of providing the most efficacious therapeutic regi mens and the best possible care for those already in their latter years. The second is to determine the cause or causes for senes cence and all its attendant problems in order to decrease the im pact of senescence on general health and well being. This volume is aimed at examining possible relationships be tween biological time structure and aging and ways by which these interrelationships might be examined in terms of both the causes of senescence and the management of health problems of the elderly. The purpose of the volume is to stir the interests of chronobiolo gists in gerontology and those of gerontologists and geriatricians in chronobiology.
Erscheinungsdatum: 22.01.2013

lgrsnf/A:\Springer\bok%3A978-1-4757-4460-6.pdf

nexusstc/Aging and Biological Rhythms/3ed5c9cf4fc933ac089087724eb53f5c.pdf

zlib/Medicine/Harvey V. Samis Jr. (auth.), Harvey V. Samis Jr., Salvatore Capobianco (eds.)/Aging and Biological Rhythms_2250513.pdf

Harvey V Samis; Salvatore Capobianco; Eckerd College Gerontology Center; Geriatric Research, Education and Clinical Center

Springer London, Limited

Plenum Press

Advances in experimental medicine and biology, 108, Boston, MA, 1978

Advances in experimental medicine and biology, New York, ©1978

United States, United States of America

Jan 22, 2013

1, 2013

lg1081549

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Source title: Aging and Biological Rhythms (Advances in Experimental Medicine and Biology)

Aging is one of the most serious and costly health problems in the Western world. A disproportionate amount of the available health care capability is devoted to the health care of the aged and the cost of this care is soaring. Viewed in wide perspective, aging presents two problems for the researcher's consideration. First is that of providing the most efficacious therapeutic regimens and the best possible care for those already in their latter years. The second is to determine the cause or causes for senescence and all its attendant problems in order to decrease the impact of senescence on general health and well being. This volume is aimed at examining possible relationships between biological time structure and aging and ways by which these interrelationships might be examined in terms of both the causes of senescence and the management of health problems of the elderly. The purpose of the volume is to stir the interests of chronobiologists in gerontology and those of gerontologists and geriatricians in chronobiology. It is indisputable, in our judgment, that biological time structure is a mutable dimension of biological organization with adaptive capability which is endogenously derived and exogenously cued. Its effects extend from the level of the cell to the interactions of the organism with its environment. Its characteristics affect an organism's response to stress and environmental insults as well as to remedial intervention. It is a dimension of organization whose properties and susceptibility to change have been largely ignored in the context of aging. The contributors of this volume have approached the problem from vastly different points of view. Some have focused on cellular mechanisms; others on integrated systems and total organism effects. Some have stressed the effects of advancing age on time structure; others have concentrated on possible ways by which deterioration in time structure might be translated and amplified to affect deterioration in functional potential. They have probed for new approaches and suggested modes of attack. They have laid the foundation for a new area of gerontological research which may be called chronogerontology

Front Matter....Pages i-x
Introduction....Pages 1-4
Chronobiologic Optimization of Aging....Pages 5-56
Significance of the Chronobiological Approach in Carrying Out Aging Studies....Pages 57-96
Phase Shifting and Life Span in the Codling Moth, Laspeyresia Pomonella (L)....Pages 97-99
Aging in the Circadian Time Structure of Blood Cell Titers in the Rat....Pages 101-103
Age Changes in Rhythms of Energy Metabolism, Activity, and Body Temperature in Mus and Peromyscus ....Pages 105-124
Clocked Cell Cycle Clocks: Implications Toward Chronopharmacology and Aging....Pages 125-184
Circadian Dyschronism and Chronotypic Ecophilia as Factors in Aging and Longevity....Pages 185-213
Interrelations Between Biological Rhythms and Clocks....Pages 215-234
Biologic Rhythms and Sympathetic Neural Control of Pineal Metabolism....Pages 235-249
Circadian Organization and Female Reproductive Cyclicity....Pages 251-274
Circadian Rhythms in the Central Cholinergic System in Aging Animals....Pages 275-299
Age Related Circadian Responsiveness of MAO Inhibitors....Pages 301-308
Sleep, Biological Rhythms and Aging....Pages 309-323
Concluding Comments....Pages 325-327
Epilogue....Pages 329-332
Back Matter....Pages 333-342

2013-12-12