The Study Of Dna Advanced Human Knowledge In A Way Comparable To The Major Theories In Physics, Surpassed Only By Discoveries Such As Fire Or The Number Zero. However, It Also Created Conceptual Shortcuts, Beliefs And Misunderstandings That Obscure The Natural Phenomena, Hindering Its Better Understanding. The Deep Conviction That No Human Knowledge Is Perfect, But Only Perfectible, Should Function As A Fair Safeguard Against Scientific Dogmatism And Enable Open Discussion. With This Aim, This Book Will Offer To Its Readers 30 Chapters On Current Trends In The Field Of Dna Replication. As Several Contributions In This Book Show, The Study Of Dna Will Continue For A While To Be A Leading Front Of Scientific Activities.

lgli/_459345.545e7b7da52d2f4ec31f96b8bec5e820.pdf

lgrsnf/_459345.545e7b7da52d2f4ec31f96b8bec5e820.pdf

zlib/Biology and other natural sciences/Hervé Seligmann/DNA REPLICATION - CURRENT ADVANCES_1181695.pdf

Bacterial Genetics of Large Mammalian DNA Viruses: Bacterial Artificial Chromosomes as a Prerequisite for Efficiently Studying Viral DNA Replication and Functions

Relationship Between Fork Progression and Initiation of Chromosome Replication in E. Coli

Faithful DNA Replication Requires Regulation of CDK Activity by Checkpoint Kinases

Eukaryote Dna Replication and Recombination An intimate Association

Eukaryotic Replication Barriers How, Why and Where Forks Stall

Elena C. Guzmán; Alfonso Jiménez-Sánchez; Carmen Mata Martín; Elena López Acedo; Estrella Guarino; Israel Salguero; Ma Antonia Sánchez-Romero; Vic Norris

Felix Wussow; Anne Brunnemann; Helmut Fickenscher; Linda Hüske; Tanja Spieckermann; Tuna Toptan

Claus Storgaard Sørensen; Halfdan Beck; Randi G. Syljuåsen; Viola Nähse-Kumpf

Ramsay J McFarlane

Jacob Z Dalgaard

Herve Seligmann

In Tech d.o.o.

Croatia, Croatia

Aug 01, 2011

s.l, 2011

2011 12 30

lg743669

{"isbns":["9533075937","9789533075938"],"last_page":708,"publisher":"InTech"}

Source title: DNA Replication: Current Advances

preface_ DNA Replication-Current Advances......Page 1
Part 1......Page 15
01_DNA Structure: Alphabet Soup for the Cellular Soul......Page 17
02_Replication Demands an Amendment of the Double Helix......Page 43
03_Phosphorothioation: An Unusual Post-Replicative Modification on the DNA Backbone......Page 71
04_Mitosis and DNA Replication and Life Origination Hydrate Hypotheses: Common Physical and Chemical Grounds......Page 89
Part 2......Page 129
05_Strand-specific Composition Bias in Bacterial Genomes......Page 131
06_Mutation Patterns Due to Converging Mitochondrial Replication and Transcription Increase Lifespan, and Cause Growth Rate-Longevity Tradeoffs......Page 151
07_Mitochondrial DNA Replication in Health and Disease......Page 181
08_Damage and Replication Stress Responses......Page 197
Part 3......Page 215
09_Relationship between Fork Progression and Initiation of Chromosome Replication in E. coli......Page 217
10_Replication Origin Selection and Pre-Replication Complex Assembly......Page 235
11_The Coordination between DNA Replication Initiation and Other Cell Cycle Events......Page 247
12_The Organisation of Replisomes......Page 267
13_Eukaryotic Replication Barriers: How, Why and Where Forks Stall......Page 283
14_Control of Telomeric DNA Replication: Genetics, Molecular Biology, and Physiology......Page 319
15_Telomere Maintenance in Organisms without Telomerase......Page 337
16_Eukaryote DNA Replication and Recombination: an Intimate Association......Page 361
Part 4......Page 403
17_Cell Cycle Regulation of DNA Replication in S. cerevisiae......Page 405
18_Free Histones and the Cell Cycle......Page 423
19_Involvement of Linker Histones in the Regulation of Replication Timing......Page 441
20_Replication Timing: Evolution, Nuclear Organization and Relevance for Human Disease......Page 451
21_The Silencing Face of DNA Replication: Gene Repression Mediated by DNA Replication Factors......Page 481
Part 5......Page 499
22_Faithful DNA Replication Requires Regulation of CDK Activity by Checkpoint Kinases......Page 501
23_Regulation of the G1/S Transition in Adult Liver: Expression and Activation of the Cyclin Dependent Kinase Cdk1 in Differentiated Hepatocytes is Controlled by Extracellular Signals and is Crucial for Commitment to DNA Replication......Page 525
24_Binding of Human MCM-BP with MCM2-7 Proteins......Page 563
25_DNA Replication in Animal Systems Lacking Thioredoxin Reductase I......Page 579
Part 6......Page 599
26_Prevalence of Reactivation of Hepatitis B Virus DNA Replication in Rheumatoid Arthritis Patients......Page 601
27_Oncogenic Aspects of HPV Infections of the Female Genital Tract......Page 609
28_The Role of E2 Proteins in Papillomavirus DNA Replication......Page 627
29_Topoisomerase I and II Expression in Recurrent Colorectal Cancer Cells: A Dubious Matter......Page 653
30_Bacterial Genetics of Large Mammalian DNA Viruses: Bacterial Artificial Chromosomes as a Prerequisite for Efficiently Studying Viral DNA Replication and Functions......Page 683

2012-02-04