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Transducing the Genome : Information, Anarchy, and Revolution in the Biomedical Sciences 🔍
Gary Zweiger McGraw-Hill Companies, 1st edition, January 17, 2001
英语 [en] · PDF · 2.2MB · 2001 · 📘 非小说类图书 · 🚀/lgli/lgrs/nexusstc/zlib · Save
描述
"Captivating... hard to put down." ­­ Choice
"A bracing insider's account of why gene structure matters to science and commerce." ­­ American Scientist
How genomics is bringing biology into the Digital Age
In this important book, a scientist gives us an inside account of the historic paradigm shift under way in the life sciences as a result of the Human Genome Project and provides a philosophical framework in which to understand biology and medicine as information sciences. In a story told on many fascinating levels, Gary Zweiger introduces us to the visionaries who first understood genes as information carriers and chronicles how their early efforts led to the birth of the new science of genomics. He provides insights into the uneasy collaboration of private, government, and academic efforts, the role of the pharmaceutical companies, and the influence of venture capitalists on one of the most ambitious and potentially significant scientific undertakings in history. Most important, he explores the profound impact that the transducing of biological information into a digital format already has had on biological research and medicine, and the equally profound effect it is sure to have on our understanding of ourselves and all living creatures.
备用文件名
nexusstc/Transducing the Genome: Information Anarchy and Revolution in the Biomedical Sciences/562967f269e4250862c16893dfe0a160.pdf
备用文件名
zlib/Biology and other natural sciences/Gary Zweiger/Transducing The Genome: Information, Anarchy, and Revolution in the Biomedical Sciences_605882.pdf
备选作者
Zweiger, Gary
备用出版商
McGraw-Hill Professional Publishing
备用出版商
McGraw-Hill School Education Group
备用出版商
Irwin Professional Publishing
备用出版商
McGraw Hill LLC
备用出版商
Oracle Press
备用版本
McGraw Hill LLC Professional Division, New York, 2001
备用版本
United States, United States of America
备用版本
First Edition, US, 2001
备用版本
Blacklick, USA, 2001
备用版本
1st, 2002
元数据中的注释
0
元数据中的注释
lg178331
元数据中的注释
{"edition":"1","isbns":["0071369805","0071381333","0071387617","9780071369800","9780071381338","9780071387613"],"last_page":288,"publisher":"McGraw-Hill"}
备用描述
EEn......Page 0
Transducing The Genome - Information, Anarchy, and Revolution in the Biomedical Sciences......Page 1
Copyright Info......Page 4
TOC......Page 5
Acknowledgments......Page 6
Introduction......Page 8
1 - Cancer, Computers, and a "List-Based" Biology......Page 15
2 - Information and Life......Page 26
3 - Behold the Gene......Page 34
4 - Working with Genes One at a Time......Page 43
5 - The Database......Page 50
6 - Getting the Genes......Page 58
7 - Prospecting for Genes with ESTs......Page 72
8 - ESTs, the Gene Race, and Moore's Law......Page 87
9 - The End Game......Page 97
10 - Human Genome History......Page 114
11 - Comparing Human Genomes......Page 125
12 - A Paradigm in Peril......Page 133
13 - The Ancient Internet--Information Flow in Cells......Page 143
14 - Accessing the Information Output of the Genome......Page 157
15 - The Genomics Industry......Page 169
16 - The SNP Race......Page 184
17 - From Information to Knowledge......Page 195
18 - The Final Act......Page 207
Appendix - How the Patent Process Works......Page 227
Glossary......Page 241
Notes......Page 245
Index......Page 264
About the Author......Page 275
备用描述
In this important book, a scientist gives us an inside account of the historic paradigm shift underway in the life sciences as a result of The Human Genome Project, and provides a philosophical framework in which to understand biology and medicine as information sciences. In a story told on many fascinating levels, Gary Zweiger introduces us to the visionaries who first understood genes as information carriers and chronicles how their early efforts led to the birth of the new science of genomics.
He provides insights into the uneasy collaboration of private, government, and academic efforts, the role of the pharmaceutical companies, and the influence of venture capitalists on one of the most ambitious and potentially significant scientific undertakings in history. Most importantly, he explores the profound impact that the transducing of biological information into a digital format already has had on biological research and medicine, and the equally profound effect it is sure to have on our understanding of ourselves and all living creatures.
备用描述
"In Transducing the Genome, geneticist Gary Zweiger provides us with our most lucid explanation yet of the significance of the Human Genome Project and the dramatic paradigm shift that it has engendered in the life sciences. He explains how the marriage of information technology and biology necessitated by the race to sequence the human genome has led to the emergence of genomics, a revolutionary new science that provides unprecedented access to the processes of life.
Going beyond the traditional one-gene-one-trait approach, genomics transduces biological data into digital information, which then can be analyzed and manipulated using powerful computer algorithms, data mining tools, and other advanced information technologies to reveal meaningful patterns among vast networks of millions of life's molecules."--BOOK JACKET.
备用描述
Science is about providing truthful explanations and trustworthy predictions to an otherwise poorly understood and unpredictable world.
开源日期
2010-01-07
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