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[Research and Perspectives in Endocrine Interactions] Multiple Origins of Sex Differences in Brain || 🔍
Khatuna Gagnidze, Donald W. Pfaff (auth.), Donald W. Pfaff, Yves Christen (eds.) Springer Berlin Heidelberg : Imprint : Springer, 10.1007/97, 2013
英语 [en] · PDF · 3.3MB · 2013 · 📘 非小说类图书 · 🚀/lgli/scihub/upload/zlib · Save
描述
In theoretical terms, sex differences in brains and behaviors of laboratory animals offer the possibility of fascinating scientific studies on a range of molecular phenomena such as genomic imprinting, DNA methylation, chromatin protein modification, non-coding DNA, potentially resulting in important neuroanatomical and neurochemical sex differences in the brain. Such sex differences could arise consequent to exposures to testosterone early in development, or to other effects deriving from the Y chromosome. However, this general subject has been treated with much hyperbole. Historically, sex differences were assumed to be present where they did not really exist, e.g. with respect to mathematics, executive leadership, etc. etc. Under what circumstances do we really care about sex differences in brain and behavior? These circumstances concern human maladies whose diagnoses are much different between boys and girls, or between women and men. Prominent examples discussed in this volume include autism, attention deficit hyperactivity disorders and congenital adrenal hyperplasia. In fact, infant boys are more susceptible than infant girls to a variety of disorders that arise early in development. This volume then ends with a consideration of effects of estrogenic hormones on the injured brain, and their roles as protective agents.
备用文件名
scihub/10.1007/978-3-642-33721-5.pdf
备用文件名
zlib/no-category/Pfaff, Donald W.; Christen, Yves/[Research and Perspectives in Endocrine Interactions] Multiple Origins of Sex Differences in Brain ||_66358800.pdf
备选标题
Multiple Origins of Sex Differences in Brain: Neuroendocrine Functions and their Pathologies (Research and Perspectives in Endocrine Interactions)
备选作者
Donald W Pfaff; Yves Christen; SpringerLink (Online service)
备选作者
Pfaff, Donald W.; Christen, Yves
备用出版商
Spektrum Akademischer Verlag. in Springer-Verlag GmbH
备用出版商
Steinkopff. in Springer-Verlag GmbH
备用出版商
Springer London, Limited
备用版本
Research and perspectives in endocrine interactions, 1st ed. 2013, Berlin, Heidelberg, 2013
备用版本
Research and perspectives in endocrine interactions, Berlin ; New York, ©2013
备用版本
Springer Nature, Berlin, 2013
备用版本
Germany, Germany
元数据中的注释
sm34015858
元数据中的注释
producers:
Acrobat Distiller 9.4.5 (Windows)
备用描述
Multiple Origins of Sex Differences in Brain 4
Neuroendocrine Functions and their Pathologies 4
Foreword 6
Acknowledgments 8
Contents 10
Contributors 12
Hormone-Dependent Chromatin Modifications Related to Sexually Differentiated Behaviors 15
Importance of Genomic Imprinting in the Evolution and Development of the Maternal Brain 34
Genomic Imprinting in the Adult and Developing Brain 47
The Synapse: Differences Between Men and Women 54
Gonadal Hormone Influences on Human Neurobehavioral Development: Outcomes and Mechanisms 69
Congenital Adrenal Hyperplasia: Neuroendocrine, Behavioral and Cognitive Implications 80
Genetic Variation Within Serotonin Genes, Hormones, and Aggression 89
Multiple Origins of Sex Differences in Attention Deficit Hyperactivity Disorder 111
Fetal Testosterone in Mind: Implications for Autism 131
Sex Differences in HPA and HPG Axes Dysregulation in Major Depressive Disorder: The Role of Shared Brain Circuitry Between Hormones and Mood 146
Estrogens: Protective or Risk Factors in the Injured Brain? 171
Index 185
备用描述
In theoretical terms, sex differences in brain and behavior offer the possibility of fascinating scientific studies on a range of molecular phenomena such as DNA methylation, chromatin protein modification, non-coding DNA, resulting in important neuroanatomical and neurochemical effects. However, this general subject has been treated with much hyperbole. Historically, sex differences were assumed to be present where they did not really exist, e.g. with respect to mathematics, executive leadership, etc. etc. Under what circumstances do we really care about sex differences in brain and behavior? These circumstances concern human maladies whose diagnoses are much different between boys and girls, or between women and men. Prominent examples to be discussed today will include autism, attention deficit hyperactivity disorders and congenital adrenal hyperplasia. The meeting will end with a consideration of effects of estrogenic hormones on the injured brain, and their roles as protective agents.
开源日期
2015-07-30
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