Myb Transcription Factors: Their Role in Growth, Differentiation and Disease (Proteins and Cell Regulation (2)) 🔍
Colin Davidson, Emily Ray, Joseph Lipsick (auth.), Professor Jon Frampton (eds.) Springer Netherlands, Proteins and Cell Regulation 2, 1, 2004
英语 [en] · PDF · 8.7MB · 2004 · 📘 非小说类图书 · 🚀/lgli/lgrs/nexusstc/scihub/upload/zlib · Save
描述
This volume represents the first collection of articles contributed by research leaders working on the Myb family of transcriptional regulatory proteins. In more than twenty chapters the authors discuss the range of biological processes and diverse cell types in which Myb proteins operate. Although concentrating on the three vertebrate Myb family members, homologues from lower species are also discussed because of the light they are able to shed on the evolution and function of these proteins. Individual chapters describe the involvement of Myb proteins, in particular c-Myb, in normal and diseased development and function of many tissues including haemopoietic cells, blood vessels, the gastrointestinal tract and the brain. Several chapters explore the mechanistic details of the action of Myb proteins, especially structural features, their interaction with DNA and other regulatory proteins, and the variety of genes that are regulatory targets for this group of transcription factors. This work will be of interest to those working directly in the field and also to the wider research community investigating the transcriptional regulation of development, differentiation and growth. The therapeutic potential of manipulating Myb function is also discussed making the book appealing to clinician scientists in several fields including haematology, oncology and cardiology.
备用文件名
nexusstc/Myb Transcription Factors: Their Role in Growth, Differentiation and Disease/852ebb175d5969fa5baaadc3e7df98b3.pdf
备用文件名
lgli/10.1007%2F978-1-4020-2869-4.pdf
备用文件名
lgrsnf/10.1007%2F978-1-4020-2869-4.pdf
备用文件名
scihub/10.1007/978-1-4020-2869-4.pdf
备用文件名
zlib/Science (General)/Colin Davidson, Emily Ray, Joseph Lipsick (auth.), Professor Jon Frampton (eds.)/Myb Transcription Factors: Their Role in Growth, Differentiation and Disease_2163254.pdf
备选作者
edited by Jon Frampton
备选作者
PdfCompressor 3.1.34
备用出版商
Kluwer Academic Publishers
备用出版商
Springer London, Limited
备用出版商
Springer Nature
备用版本
Proteins and Cell Regulation -- v. 2., Dordrecht, Boston, Netherlands, 2004
备用版本
United States, United States of America
备用版本
Springer Nature, Dordrecht, 2007
备用版本
1 edition, December 31, 1899
备用版本
2004, 2005-03-11
备用版本
1, 20071013
元数据中的注释
lg1009253
元数据中的注释
producers:
CVISION Technologies
元数据中的注释
{"edition":"1","isbns":["1402027796","1402028695","9781402027796","9781402028694"],"last_page":405,"publisher":"Springer Netherlands","series":"Proteins and Cell Regulation 2"}
元数据中的注释
Includes bibliographical references.
备用描述
Front Matter....Pages i-xxxi
Evolution of Myb Proteins....Pages 1-33
Drosophila Myb....Pages 35-64
Essential And Diverse Roles For C-Myb Throughout T Cell Development....Pages 65-80
Potential Roles For C-Myb Thoughout Early Lymphocyte Development....Pages 81-105
Involvement Of C-Myb In Red Cell And Megakaryocyte Development....Pages 107-131
C-Myb As A Key Player In The Control Of Myeloid Cell Differentiation....Pages 133-144
Does C-Myb Have A Role In Haemopoietic Stem Cells And Multilineage Progenitors?....Pages 145-161
A-Myb In Development And Cancer....Pages 163-179
B-Myb: A Highly Regulated Member Of The Myb Transcription Factor Family....Pages 181-199
Regulation Of Mammalian Myb Gene Expression....Pages 201-221
The C-Myb Dna Binding Domain....Pages 223-238
Myb Partnerships....Pages 239-256
Target Genes Of V-Myb And C-Myb....Pages 257-270
The Microarray Big Bang....Pages 271-278
The V-Myb Oncogene....Pages 279-306
C-Myb And Leukaemogenesis....Pages 307-329
The Involvement Of Myb In Vascular Injury....Pages 331-349
Repression Of Matrix Gene Expression By B-Myb....Pages 351-366
The Role Of C-Myb In Gastrointestinal Tract Development And Carcinogenesis....Pages 367-388
C-Myb And Creb Function In Adult Neurogenesis....Pages 389-397
The C-Myb Gene: A Rational Target For Treatment Of Human Diseases....Pages 399-415
备用描述
Amino acid alignment of invertebrate and vertebrate 3R Myb proteins.
开源日期
2013-08-20
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