This book highlights both conventional and nanomaterials-based biosensors for the detection of cervical cancers. It describes developments in the selective and sensitive electrochemical biosensors based on DNA for the early diagnosis of cervical cancer. Further, this book covers other nano-biosensing systems such as nano-thermometry-based sensing platforms, mechanical sensing platforms encompassing piezoelectric-based sensors, electrochemical impedance spectroscopy based on PEGylated arginine functionalized magnetic nanoparticles, and field-effect transistor-based platforms for the early detection of cervical cancer. Also, it presents conventional platforms such as vibrational spectroscopy and polymerase chain reaction techniques for the diagnosis of cervical cancer. Finally, it reviews currently available biomarkers for the early diagnosis of cervical cancer and presents strategies for developing novel biomarkers based on cellular and molecular approaches. As such, this book is a comprehensive resource for researchers and clinicians working in cervical cancer diagnostics.

nexusstc/Biomarkers and Biosensors for Cervical Cancer Diagnosis/8d93a35c8f969981e5aa63b4de441147.pdf

lgrsnf/96.pdf

scihub/10.1007/978-981-16-2586-2.pdf

John Bosco Balaguru Rayappan,Jung Heon Lee (eds.)

Rayappan, John Bosco Balaguru; Lee, Jung Heon

Springer Nature Singapore Pte Ltd Fka Springer Science + Business Media Singapore Pte Ltd

Springer Nature, Singapore, 2021

Singapore, Singapore

2, 20210728

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Acknowledgments
Contents
About the Editors
1: An Introduction to Cancer Biomarkers
1.1 Introduction
1.1.1 Epidemiology and Aetiology of Cervical Cancer
References
2: Cervical Cancer
2.1 Cervical Cancer
2.2 Pathology
2.2.1 Molecular Biology: HPV Genome Organization
2.2.2 Life Cycle of HPV: Virus Replication-Latent to Productive Infection
2.2.3 Role of HPV in Cervical Cancer
2.3 Conclusion
References
3: Potential Biomarkers for Early Diagnosis of Cervical Cancer
3.1 Introduction
3.2 Molecular Markers
3.2.1 DNA Based Markers
3.2.2 RNA Based Markers
3.2.2.1 miRNA-Based Markers
3.2.2.2 circRNA-Based Markers
3.2.2.3 lncRNA-Based Markers
3.3 Protein-Based Markers
3.4 Conclusion
References
4: Methods for Screening of Cervical Cancer: State of Art
4.1 Introduction
4.2 Cytology-Based Methods
4.3 Serological Methods
4.4 Nucleic Acid-Based Methods
4.5 Conclusion
References
5: Electrochemical DNA Biosensors for Cervical Cancers
5.1 Introduction
5.2 Electrochemical Detection of Cervical Cancer
5.2.1 Label Free Detection of HPV DNA
5.2.2 Labelled (Indirect) Detection of DNA
5.3 Conclusion
References
6: Optical DNA Based Sensors for Cervical Cancers
6.1 Introduction
6.2 Fluorescent Biosensors
6.3 Colorimetric Biosensor
6.4 Conclusion
References
7: Other Biosensors for Cervical Cancer Detection
7.1 Introduction
7.2 Temperature Based Detection
7.2.1 Nanothermometry
7.3 Vibrational Spectroscopy-Based Detection Strategies
7.3.1 Infrared Spectroscopy-Based Detection
7.3.2 Raman Spectroscopy-Based Detection
7.4 FET Based Sensors
7.5 Mechanical Biosensors
7.6 PCR Biosensors
7.7 Other Optical Biosensors
7.8 Conclusion
References

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Erscheinungsdatum: 29.07.2021

2021-10-10