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Erscheinungsdatum: 05.10.2011

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zlib/Medicine/J. G. Schenker, S. Mor-Yosef (auth.), B. Runnebaum, T. Rabe, L. Kiesel (eds.)/Future Aspects in Contraception: Proceedings of an International Symposium held in Heidelberg, 5–8 September 1984 Part 2 Female Contraception_2239673.pdf

Future Aspects in Contraception : Proceeding of an International Symposium held in Heidelberg, 5-8 September 1984 Part 1 Male Contraception

B. Runnebaum, B. Runnebaum, T. Rabe, L. Kiesel

B. Runnebaum, T. Rabe, L. Kiesel, B. Runnebaum

Springer; L Kiesel B Runnebaum T Rabe

Springer Science + Business Media BV

Springer Nature, Dordrecht, 2012

Netherlands, Netherlands

Oct 05, 2011

1, 2011

lg1070707

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Source title: Future Aspects in Contraception: Proceedings of an International Symposium Held in Heidelberg, 5-8 September 1984 Part 2 Female Contraception

Front Matter....Pages i-xii
Natural family planning....Pages 1-14
Barrier methods of contraception....Pages 15-22
Chemistry, contraceptive activity and toxicology of aryl guanidinobenzoates: inhibitors of sperm acrosin....Pages 23-29
Measurement of LH in saliva; a new approach to ovulation detection....Pages 31-47
Steroid-induced side-effects of oral contraceptives....Pages 49-62
Efficacy and physiology of a triphasic oral contraceptive....Pages 63-69
Advantages and disadvantages of low-dose hormonal contraceptive agents....Pages 71-82
Emerging routes of delivery for fertility-control agents....Pages 83-93
Current status of NORPLANT subdermal implants for contraception....Pages 95-106
New aspects in post-coital contraception....Pages 107-113
Biological evaluation of some medicinal plant extracts for contraceptive efficacy in females....Pages 115-128
Pharmacokinetic and antigenicity studies with LHRH analogues....Pages 129-147
LHRH nasal spray in contraception....Pages 149-160
Acute and intermittent LHRH agonist dosing as post-coital and anti-ovulatory contraceptive approaches....Pages 161-175
LHRH antagonists and contraception....Pages 177-187
Mechanism of action of gonadotrophin releasing hormone in the pituitary and gonads....Pages 189-201
Morphological changes on the surface of IUDS: Are they of clinical significance?....Pages 203-227
The use of non-culture tests for the detection of VD prior to IUD insertion: a view towards the future....Pages 229-234
Experience with GYNE-T Cu-380-A intrauterine contraceptive device (1981–1984)....Pages 235-237
Ten years’ experience with continuous use of the butterfly IUD....Pages 239-244
The antiprogesterone activity of RU 486, a contragestive agent in the human....Pages 245-248
Effects of the antiprogesterone RU 486 in early pregnancy and during the menstrual cycle....Pages 249-270
Prostaglandins in contraception....Pages 271-279
Ovarian hormones and cybernins....Pages 281-288
Biochemical aspects of a contraception model based on immunological properties of proteohormones....Pages 289-304
Variability in antisperm and antiembryonic humoral immune responses....Pages 305-317
Research for the development of an hCG antifertility vaccine....Pages 319-331
Present and future aspects of immunological methods in contraception....Pages 333-341
Preclinical and clinical aspects of safety in contraception....Pages 343-349
The politics of contraception....Pages 351-360
Contraceptive futurology: or 1984 in 1984....Pages 361-368
Back Matter....Pages 369-372

Atrophy of gonadotrophin producing cells Exogenously LH synthesis administered androgens and release or anabolic steroids are decreased Prostate Testes Normal function. Testosterone synthesis in The deficit of endogenously Leydig cells is decreased. The synthesized testosterone is exogenously administered compensated for by the steroid is not able to exogenously administered compensate for the deficit of steroid endogenously synthesized testosterone Figure 2 Intratesticular and serum testosterone concentrations after treatment with andro gens or anabolic steroids in order to substitute for the peripheral androgen deficiency and to achieve azoospermia. Because this steroid is alkylated in position 17, toxic effects on liver function can not be excluded. Danazol offers no advantages as compared with other anabolic steroids; rather, disadvantages. Numerous experiments of this type have been performed during the last 40 or 50 years. The outcome in each case was more or less identical: with a certain dose of an androgen or anabolic steroid it is possible to inhibit spermatogenesis without interfering with other androgen-dependent func tions, including libido (potentia coeundi) and accessory sexual glands. On the basis of this pharmacological-endocrinological background, androgens and anabolic steroids can be used for male fertility control, and several clinical trials have been performed during the last 10-15 years. Some of 1 these studies 2-23 are mentioned in Table 2

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