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Polychlorinated Biphenyls (pcbs): Mammalian And Environmental Toxicology (environmental Toxin Series) 🔍
S. Safe, L. Safe, M. Mullin (auth.), Prof. Dr. Stephen Safe (eds.) Springer-Verlag Berlin Heidelberg, Environmental Toxin Series, Environmental Toxin Series 1, 1, 1987
英语 [en] · PDF · 3.3MB · 1987 · 📘 非小说类图书 · 🚀/lgli/lgrs/nexusstc/scihub/zlib · Save
描述
Polychlorinated biphenyls (PCBs) have been produced commercially since be fore 1930. They proved to be highly versatile mixtures and their uses continued to expand during the early 1970's even after the unanticipated world-wide en vironmental contamination had been discovered (Jensen et aI. , 1969; Koeman et aI. , 1969). Over 600,000 metric-tons were produced and/or used in the U. S. during this time and it is estimated that worldwide production totaled about 1,200,000 metric-tons (Table 1). With low acute toxicities (Fishbein, 1974), these mixtures were considered gen erally biologically inactive even though industrial exposure had demonstrated he patic and dermatological effects (Fishbein, 1974; Hansen, 1987). Thus, use and disposal were not carefully monitored and it is estimated that one-third of the world-wide production of PCBs has been released into the global environment (Table 1). Table 1. Estimated production and disposition of PCBs b U. s. a Worldwide 6 6 Production/use 610 X 10 kg 1200 X 10 kg Mobil environmental reservoir 82 400 Static reservoirs In service 340 Dumps 130 Total static 470 800 a NAS, 1979 b Tatsukawa and Tanaba, 1984 2 Environmental Distribution Many countries now impose strict controls on the use and release of PCBs. Re lease into the environment has declined dramatically in the last decade, but con tinued release from reservoirs (Table 1) into burdened ecosystems (Table 2) ap pears inevitable for several more decades (Barros et aI. , 1984).
Erscheinungsdatum: 20.11.2011
备用文件名
lgrsnf/A:\Springer\bok%3A978-3-642-70550-2.pdf
备用文件名
nexusstc/Polychlorinated Biphenyls (PCBs): Mammalian and Environmental Toxicology/a0341820fab56656eb500972002603a5.pdf
备用文件名
scihub/10.1007/978-3-642-70550-2.pdf
备用文件名
zlib/Engineering/S. Safe, L. Safe, M. Mullin (auth.), Prof. Dr. Stephen Safe (eds.)/Polychlorinated Biphenyls (PCBs): Mammalian and Environmental Toxicology_2265839.pdf
备选作者
Stephen Safe, R. L. Dedrick, L. G. Hansen, M. A. Hayes, R. J. Lutz
备用出版商
Spektrum Akademischer Verlag. in Springer-Verlag GmbH
备用出版商
Steinkopff. in Springer-Verlag GmbH
备用出版商
Springer London, Limited
备用版本
Environmental toxin series, 1, Berlin, Heidelberg, 1987
备用版本
Springer Nature, Berlin, Heidelberg, 2012
备用版本
Germany, Germany
备用版本
1, 2011
元数据中的注释
lg1096879
元数据中的注释
{"container_title":"Environmental Toxin Series","edition":"1","isbns":["3642705502","3642705529","9783642705502","9783642705526"],"issns":["0935-0209"],"last_page":152,"publisher":"Springer","series":"Environmental Toxin Series 1"}
备用描述
The concern about environmental toxins is ever increasing, as is the need for sound scientific information. The Environmental Toxin Series is dedicated to the publication of comprehensive reviews and monographs on compounds or classes of chemicals which are of importance in environmental toxicology. The series is designed to serve as a background of information for scientific investigation as well as risk analysis and political decision making. The main aim of the series is to describe in as complete a way as possible all potentially hazardous chemicals from the point of view of chemistry, ecology, toxicology, risk analysis and regulatory implications. From time to time conference proceedings on important and urgent topics will be included in the series. We thank the members of the editorial board for their enthusiastic support
备用描述
Front Matter....Pages I-X
Polychlorinated Biphenyls: Environmental Occurrence and Analysis....Pages 1-13
Environmental Toxicology of Polychlorinated Biphenyls....Pages 15-48
Mammalian Biologic and Toxic Effects of PCBs....Pages 49-75
Carcinogenic and Mutagenic Effects of PCBs....Pages 77-95
Biotransformation of PCBs: Metabolic Pathways and Mechanisms....Pages 97-110
Physiologic Pharmacokinetic Modeling of Polychlorinated Biphenyls....Pages 111-131
PCBs and Human Health....Pages 133-145
Back Matter....Pages 147-152
开源日期
2013-12-12
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