This volume details a collection of state-of-art methods including identification of novel ncRNAs and their targets, functional annotation and disease association in different biological contexts. Chapters guide readers through an overview of disease-specific ncRNAs, computational methods and workflows for ncRNA discovery, annotation based on high-throughput sequencing data, bioinformatics tools and databases for ncRNA analyses, network-based methods, and kinetic modelling of ncRNA-mediated gene regulation. Written in the highly successful __Methods in Molecular Biology__ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge, __Computational Biology of Non-Coding RNA: Methods and Protocols__ aims to provide a state-of-the-art collection of computational methods and approaches that will be of value to researchers interested in ncRNA field.

lgli/N:\!genesis\springer\pack4\10.1007%2F978-1-4939-8982-9.pdf

lgrsnf/N:\!genesis\springer\pack4\10.1007%2F978-1-4939-8982-9.pdf

nexusstc/Computational Biology of Non-Coding RNA: Methods and Protocols/cc9265f38a0b6cba62abd2a8802ebdf4.pdf

scihub/10.1007/978-1-4939-8982-9.pdf

zlib/Biology and other natural sciences/Molecular/Xin Lai, Shailendra K. Gupta, Julio Vera/Computational Biology of Non-Coding RNA: Methods and Protocols_4980872.pdf

Methods in molecular biology (Clifton, N.J.), v. 1912, New York, NY, 2019

Methods in molecular biology, 1912, 1st ed. 2019, New York, NY, 2019

Methods in molecular biology (Humana Press), New York, NY, 2019

United States, United States of America

Springer protocols, New York, NY, 2019

lg2353984

producers:
Adobe PDF Library 10.0.1

{"container_title":"Methods in Molecular Biology","edition":"1","isbns":["1493989812","1493989820","9781493989812","9781493989829"],"issns":["1064-3745","1940-6029"],"publisher":"Springer New York;Humana Press","series":"Methods in Molecular Biology 1912"}

Front Matter ....Pages i-xii
Front Matter ....Pages 1-1
ncRNAs in Inflammatory and Infectious Diseases (Leon N. Schulte, Wilhelm Bertrams, Christina Stielow, Bernd Schmeck)....Pages 3-32
p73-Governed miRNA Networks: Translating Bioinformatics Approaches to Therapeutic Solutions for Cancer Metastasis (Stella Logotheti, Stephan Marquardt, Brigitte M. Pützer)....Pages 33-52
Front Matter ....Pages 53-53
Methods for Annotation and Validation of Circular RNAs from RNAseq Data (Disha Sharma, Paras Sehgal, Judith Hariprakash, Sridhar Sivasubbu, Vinod Scaria)....Pages 55-76
Methods to Study Long Noncoding RNA Expression and Dynamics in Zebrafish Using RNA Sequencing (Samatha Mathew, Ambily Sivadas, Paras Sehgal, Kriti Kaushik, Shamsudheen K. Vellarikkal, Vinod Scaria et al.)....Pages 77-110
Workflow Development for the Functional Characterization of ncRNAs (Markus Wolfien, David Leon Brauer, Andrea Bagnacani, Olaf Wolkenhauer)....Pages 111-132
ncRNA Editing: Functional Characterization and Computational Resources (Giovanni Nigita, Gioacchino P. Marceca, Luisa Tomasello, Rosario Distefano, Federica Calore, Dario Veneziano et al.)....Pages 133-174
Computational Prediction of Functional MicroRNA–mRNA Interactions (Müşerref Duygu Saçar Demirci, Malik Yousef, Jens Allmer)....Pages 175-196
Front Matter ....Pages 197-197
Tools for Understanding miRNA–mRNA Interactions for Reproducible RNA Analysis (Andrea Bagnacani, Markus Wolfien, Olaf Wolkenhauer)....Pages 199-214
Computational Resources for Prediction and Analysis of Functional miRNA and Their Targetome (Isha Monga, Manoj Kumar)....Pages 215-250
Noncoding RNAs Databases: Current Status and Trends (Vinicius Maracaja-Coutinho, Alexandre Rossi Paschoal, José Carlos Caris-Maldonado, Pedro Vinícius Borges, Almir José Ferreira, Alan Mitchell Durham)....Pages 251-285
Front Matter ....Pages 287-287
Controllability Methods for Identifying Associations Between Critical Control ncRNAs and Human Diseases (Jose C. Nacher, Tatsuya Akutsu)....Pages 289-300
Network-Based Methods and Other Approaches for Predicting lncRNA Functions and Disease Associations (Rosario Michael Piro, Annalisa Marsico)....Pages 301-321
Integration of miRNA and mRNA Expression Data for Understanding Etiology of Gynecologic Cancers (Sushmita Paul)....Pages 323-338
Front Matter ....Pages 339-339
Quantitative Characteristic of ncRNA Regulation in Gene Regulatory Networks (Federico Bocci, Mohit Kumar Jolly, Herbert Levine, José Nelson Onuchic)....Pages 341-366
Kinetic Modelling of Competition and Depletion of Shared miRNAs by Competing Endogenous RNAs (Araks Martirosyan, Marco Del Giudice, Chiara Enrico Bena, Andrea Pagnani, Carla Bosia, Andrea De Martino)....Pages 367-409
Modeling ncRNA-Mediated Circuits in Cell Fate Decision (Xiao-Jun Tian, Manuela Vanegas Ferro, Hanah Goetz)....Pages 411-426
Modeling Long ncRNA-Mediated Regulation in the Mammalian Cell Cycle (Jomar F. Rabajante, Ricardo C. H. del Rosario)....Pages 427-445
Back Matter ....Pages 447-451

"AThis volume details a collection of state-of-art methods including identification of novel ncRNAs and their targets, functional annotation and disease association in different biological contexts. Chapters guide readers through an overview of disease-specific ncRNAs, computational methods and workflows for ncRNA discovery, annotation based on high-throughput sequencing data, bioinformatics tools and databases for ncRNA analyses, network-based methods, and kinetic modelling of ncRNA-mediated gene regulation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Computational Biology of Non-Coding RNA: Methods and Protocols aims to provide a state-of-the-art collection of computational methods and approaches that will be of value to researchers interested in ncRNA field."--Page 4 de la couverture

"This volume details a collection of state-of-art methods including identification of novel ncRNAs and their targets, functional annotation and disease association in different biological contexts. Chapters guide readers through an overview of disease-specific ncRNAs, computational methods and workflows for ncRNA discovery, annotation based on high-throughput sequencing data, bioinformatics tools and databases for ncRNA analyses, network-based methods, and kinetic modelling of ncRNA-mediated gene regulation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Computational Biology of Non-Coding RNA: Methods and Protocols aims to provide a state-of-the-art collection of computational methods and approaches that will be of value to researchers interested in ncRNA field." -- Prové de l'editor

2019-04-19