ACE inhibitors are one of the most exciting and interesting of recent medical developments. They fit the patho-physiologica1 processes of cardiovascular disease with fascinating precision and are a constant stimulus to the acquisition of greater understanding of the mechanisms involved and of the mode of action of the drugs themselves. There is still much to be learned, especially about the wider effects of the drugs, their precise mode and site of action and about differences between the different preparations. ACE inhibitors are of proven benefit to patients with chronic congestive heart failure and are the latest in the series of drugs used in the treatment of hypertension. Interest in the treatment of hypertension has paralleled the development of hypotensive drugs and the realisation that long-term prognosis could be significantly improved. The treatment of hypertension has progressed in stages following the development of a succession of increasingly effective drugs, each allowing a greater proportion of patients to be treated with fewer and fewer side-effects. First, the ganglion-blocking agents such as hexamethonium and guan ethidine transformed the outlook for patients with malignant hypertension but proved too unpleasant for routine use in other forms of hypertension.
Erscheinungsdatum: 12.10.2012

lgrsnf/A:\Springer\bok%3A978-94-011-3900-7.pdf

nexusstc/ACE Inhibitors in Hypertension/d2e8c2d2124346b81939fdf6fddb53d6.pdf

scihub/10.1007/978-94-011-3900-7.pdf

zlib/Medicine/Dr Gillian Strube, Dr George Strube (auth.)/ACE Inhibitors in Hypertension: A Guide for General Practitioners_2242512.pdf

Springer Science + Business Media BV

Springer; Brand: Springer

Springer London, Limited

Springer Nature, Dordrecht, 2012

Netherlands, Netherlands

Dordrecht, 1992

Dordrecht, 1991

Oct 12, 2012

1992, 2012

lg1073546

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<p>This is a valuable, informative review of the use of ACE inhibitors in treating hypertension in general (family) practice. It also serves as a reference for basic information on the pharmacology and mode of action of this relatively novel class of drugs. The general approach reflects the needs of practitioners by emphasizing the pragmatic view. Epidemiology and pharmacology are included in the context of what a general practitioner needs to know for the effective treatment and management of patients at risk from hypertension. The book adopts an easy-to-use layout with the frequent use of tables and charts to present complex information in an easily assimilated way.</p>

Front Matter....Pages i-v
Introduction....Pages 1-2
Physiology....Pages 3-15
Cardiac and vascular implications of hypertension: the need for treatment....Pages 17-29
Diagnosis and assessment of essential hypertension....Pages 31-41
The management of patients with hypertension....Pages 43-54
The ACE inhibitor drugs: history and pharmacology....Pages 55-67
Safety and side-effects of ACE inhibitors....Pages 69-73
Special patient groups....Pages 75-95
Combination therapy with ACE inhibitors....Pages 97-98
Conclusion....Pages 99-100
Back Matter....Pages 101-107

2013-12-12