**__Frank discussions of opportunities and challenges point the way to new, more effective drug delivery systems__**
Interest in nanomedicine has grown tremendously, fueled by the expectation that continued research will lead to the safe, efficient, and cost-effective delivery of drugs or imaging agents to human tissues and organs. The field, however, has faced several challenges attempting to translate novel ideas into clinical benefits. With contributions from an international team of leading nanomedicine researchers, this book provides a practical assessment of the possibilities and the challenges of modern nanomedicine that will enable the development of clinically effective nanoparticulate drug delivery products and systems.
__Nanoparticulate Drug Delivery Systems__ focuses on the rationales and preclinical evaluation of new nanoparticulate drug carriers that have yet to be thoroughly reviewed in the literature. The first chapter sets the stage with a general overview of targeted nanomedicine. The book then explores new and promising nanoparticulate drug delivery systems, including:
* Lipid nanoparticles for the delivery of nucleic acids
* Multifunctional dendritic nanocarriers
* Polymer drug nanoconjugates
Next, the book presents new opportunities and challenges for nanoparticulate drug delivery systems, including:
* Clearance of nanoparticles during circulation
* Drug delivery strategies for combatting multiple drug resistance
* Toxicological assessment of nanomedicine
Chapters offer state-of-the-technology reviews with extensive references to facilitate further investigation. Moreover, each chapter concludes with an expert assessment of remaining challenges, pointing the way to solutions and new avenues of research.
With its frank discussions of opportunities and challenges, __Nanoparticulate Drug Delivery Systems__ sets a solid foundation for new research leading to the discovery and development of better nanomedicines.

lgli/64.Nanoparticulate Drug Delivery Systems Strategies, Technologies,.pdf

lgrsnf/64.Nanoparticulate Drug Delivery Systems Strategies, Technologies,.pdf

zlib/Engineering/Yoon Yeo/Nanoparticulate Drug Delivery Systems: Strategies, Technologies, and Applications_2528909.pdf

John Wiley & Sons, Inc., Hoboken, New Jersey, 2013

United States, United States of America

Hoboken, New Jersey, New Jersey, 2013

0

lg1336260

{"edition":"1","isbns":["1118148878","9781118148877"],"last_page":324,"publisher":"Wiley"}

Includes bibliographical references and index.

<p class="null1">Frank discussions of opportunities and challenges point the way to new, more effective drug delivery systems</p>
<p>Interest in nanomedicine has grown tremendously, fueled by the expectation that continued research will lead to the safe, efficient, and cost-effective delivery of drugs or imaging agents to human tissues and organs. The field, however, has faced several challenges attempting to translate novel ideas into clinical benefits. With contributions from an international team of leading nanomedicine researchers, this book provides a practical assessment of the possibilities and the challenges of modern nanomedicine that will enable the development of clinically effective nanoparticulate drug delivery products and systems.</p>
<p><i>Nanoparticulate Drug Delivery Systems</i> focuses on the rationales and preclinical evaluation of new nanoparticulate drug carriers that have yet to be thoroughly reviewed in the literature. The first chapter sets the stage with a general overview of targeted nanomedicine. The book then explores new and promising nanoparticulate drug delivery systems, including:</p>
<ul>
<li>Lipid nanoparticles for the delivery of nucleic acids</li>
<li>Multifunctional dendritic nanocarriers</li>
<li>Polymer drug nanoconjugates</li>
</ul>
<p>Next, the book presents new opportunities and challenges for nanoparticulate drug delivery systems, including:</p>
<ul>
<li>Clearance of nanoparticles during circulation</li>
<li>Drug delivery strategies for combatting multiple drug resistance</li>
<li>Toxicological assessment of nanomedicine</li>
</ul>
<p>Chapters offer state-of-the-technology reviews with extensive references to facilitate further investigation. Moreover, each chapter concludes with an expert assessment of remaining challenges, pointing the way to solutions and new avenues of research.</p>
<p>With its frank discussions of opportunities and challenges, <i>Nanoparticulate Drug Delivery Systems</i> sets a solid foundation for new research leading to the discovery and development of better nanomedicines.</p>

"The use of nanoparticles to deliver drugs to specific cells has substantially increased. This guide offers a thorough, up-to-date reference on nanotechnologies for drug delivery, frankly discussing challenges and limitations with nanoparticulate drug delivery systems. After discussing strategies to further develop these systems, chapters focus on applications like nanoparticles for topical drug delivery and nanomedicine toxicology, along with new techniques and methodologies like NanoCrystal. This up-to-date book offers an invaluable reference to any pharmaceutical researcher interested in nanomedicine"--
"This book provides an overview of nanoparticulate drug delivery systems, their potential applications and limitations. The chapters focus on new approaches, manufacturing methodologies, and applications of nanotechnology in drug delivery"--

"The use of nanoparticles to deliver drugs to specific cells has substantially increased. This guide offers a thorough, up-to-date reference on nanotechnologies for drug delivery, frankly discussing challenges and limitations with nanoparticulate drug delivery systems. After discussing strategies to further develop these systems, chapters focus on applications like nanoparticles for topical drug delivery and nanomedicine toxicology, along with new techniques and methodologies like NanoCrystal. This up-to-date book offers an invaluable reference to any pharmaceutical researcher interested in nanomedicine"-- Provided by publisher

"This book provides an overview of nanoparticulate drug delivery systems, their potential applications and limitations. The chapters focus on new approaches, manufacturing methodologies, and applications of nanotechnology in drug delivery"-- Provided by publisher

2015-04-26