This volume is a collection of the lectures and commu­ nications presented at the Nato Advanced Study Institute on "Liver, Nutrition and Bile Acids" held in Maratea, Italy, September 1983. The research areas covered by the Meeting are very wide, having to do with the liver and biliary pathophysiology, nutrition, gallstone disease and atherosclerosis prevention. Scientists from the major clinical and basic disciplines provided an update overview of the complex mechanisms regula­ ting the biosynthesis and catabolism of cholesterol and the formation and metabolism of bile acids. The NATO ASI has given the opportunity for thorough general discussions on problems of growing interest in medical sciences in the spirit of the NATO Meetings. This wealth of information is reflected in the present collection. We are grateful to all the contributors for the pre­ sentation of the results of their research. A particular thanks is addressed to Mrs. Brita Rolander Chilo of the Nutrition Foundation of Italy for her invaluable advice and for the organization of the Institute as well as for the editorial work. Giovanni Gall,i Enrica Bosisio v CONTENTS Coordinate Regulation of the Three Enzymes in Cholesterol Biosynthesis • •••••• 1 Ajit Sanghvi Microsomal Cholesterol 7a-Hydroxylase Phosphatases.

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NATO Advanced Study Institute on Liver, Nutrition, and Bile Acids

Plenum Press

Nato Science Series A:, Life Sciences, 90, Boston, MA, 1985

NATO ASI series, v. 90, New York, ©1985

United States, United States of America

Springer Nature, New York, NY, 2013

NATO ASI series, Boston, MA, 1985

May 06, 2012

1, 2012

decrypted from 2CE9BC89BA4CEB018078C6ACB88F24EA source file

lg2777692

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Source title: Liver, Nutrition, and Bile Acids (Nato Science Series A:)

Front Matter....Pages i-ix
Coordinate Regulation of the Three Enymes in Cholesterol Biosynthesis....Pages 1-13
Microsomal Cholesterol 7α -Hydroxylase Phosphatases....Pages 15-17
Bile Acids and Cholesterol Absorption....Pages 19-33
Regulation of Cholesterol Absorption in Humans....Pages 35-63
Biochemical Methods for Serum Bile Acid Analysis....Pages 65-80
Diagnostic Usefulness of Serum Bile Acid Determination in Liver Diseases....Pages 81-85
Quantitation and Metabolism of Bile Acids in Hyperlipoproteinemias....Pages 87-100
Effects of Lipid Lowering Diets and of Bile Acid Sequestrants on Plasma Lipoproteins and Biliary Metabolism....Pages 101-112
Fecal Bile Acids in Health and Disease....Pages 113-130
Bile Acids and Intestinal Pathophysiology....Pages 131-141
The Therapy of Cholesterol Gallstones with Bile Acids....Pages 143-149
Dissolution of Cholesterol Gallstones in Bile....Pages 151-160
Bile Acids, Fiber and Cancer....Pages 161-169
Intestinal Operations and Bile Acids: Their Effects on Adaptation and Carcinogenesis in the Gut....Pages 171-183
Similarities and Differences Between Primary Biliary Cirrhosis and Primary Sclerosing Cholangitis....Pages 185-194
Liver Transplantation : After 20 Years of Experience the Procedure Has Come of Age....Pages 195-203
Effects of Inhibitors of Cholesterol Biosynthesis in Isolated Rat Hepatocytes....Pages 205-208
Bile Acid Synthesis by Cultured Hepatocytes Regulation by Cholesterol Availability....Pages 209-218
Maturation of Bile Acid Uptake in Freshly Isolated Hepatocytes from Fetal and Newborn Rabbits....Pages 219-224
Sulfated Lithocholic Acid Conjugates and Cholestasis: Clinical Implications and Protecting Factors....Pages 225-234
Abnormal Fecal Bile Acid Excretion in Cystic Fibrosis: Physiopathological Mechanism and Clinical Implications....Pages 235-240
Effect of Chenodeoxycholic and Ursodeoxycholic Acid Treatment on Intestinal Microflora of Patients with Cholesterol Gallstones....Pages 241-247
The Influence of a Lactovegetarian, a Vegan and a Mixed Diet on Colonic Function of Man: Preliminary Results....Pages 249-252
Back Matter....Pages 253-259

NATO Science Series A:
Erscheinungsdatum: 06.05.2012

2020-08-30